منابع مشابه
Rod temporal channels
Mechanisms underlying rod temporal contrast sensitivity have been considered in terms of a fast retinal signal predominating at mesopic levels and a slower retinal signal predominating at scotopic levels. Here we use a small signal masking method, which has previously been used to delineate the cone-mediated cortical temporal channels, to investigate their rod-mediated cortical counterparts. Th...
متن کاملTemporal analysis of electroretinographic responses in fishes with rod-dominated and mixed rod-cone retina.
Photoreceptor content of fish retinas could be accessed by comparative electroretinographic (ERG) studies using flickering light stimuli that could separate rod-mediated vision where critical flicker frequency (CFF, frequency when the eye loses its ability to resolve individual light pulses) is usually less than 15 Hz from cone-mediated vision. Four fish species inhabiting different photic envi...
متن کاملMechanism of Allosteric Modulation of Rod Cyclic Nucleotide–gated Channels
The cyclic nucleotide-gated (CNG) channel of retinal rod photoreceptor cells is an allosteric protein whose activation is coupled to a conformational change in the ligand-binding site. The bovine rod CNG channel can be activated by a number of different agonists, including cGMP, cIMP, and cAMP. These agonists span three orders of magnitude in their equilibrium constants for the allosteric trans...
متن کاملcGMP-gated Ion Channels of Intact Rod and Cone Photoreceptors
The selectivity for Ca 2 1 over Na 1 , PCa/PNa, is higher in cGMP-gated (CNG) ion channels of retinal cone photoreceptors than in those of rods. To ascertain the physiological significance of this fact, we determined the fraction of the cyclic nucleotide–gated current specifically carried by Ca 2 1 in intact rods and cones. We activated CNG channels by suddenly ( , 5 ms) increasing free 8Br-cGM...
متن کاملVoltage-gated channels and calcium homeostasis in mammalian rod photoreceptors.
Recent reports on rod photoreceptor neuroprotection by Ca2+ channel blockers have pointed out the need to assess the effect of these blockers on mammalian rods. However, in mammals, rod electrophysiological characterization has been hampered by the small size of these photoreceptors, which were instead extensively studied in nonmammalian vertebrates. To further characterize ionic conductances a...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Vision Research
سال: 1996
ISSN: 0042-6989
DOI: 10.1016/0042-6989(96)89254-6